Package: SimDissolution
Type: Package
Title: Modeling and Assessing Similarity of Drug Dissolutions Profiles
Version: 0.1.0
Author: Kathrin Moellenhoff
Maintainer: Kathrin Moellenhoff <kathrin.moellenhoff@rub.de>
Description: Implementation of a model-based bootstrap approach for
        testing whether two formulations are similar. The package
        provides a function for fitting a pharmacokinetic model to
        time-concentration data and comparing the results for all five
        candidate models regarding the Residual Sum of Squares (RSS).
        The candidate set contains a First order, Hixson-Crowell,
        Higuchi, Weibull and a logistic model. The assessment of
        similarity implemented in this package is performed regarding
        the maximum deviation of the profiles. See Moellenhoff et al.
        (2018) <doi:10.1002/sim.7689> for details.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
Depends: dplyr, alabama, mvtnorm, graphics
RoxygenNote: 6.1.1
NeedsCompilation: no
Packaged: 2026-10-10 14:28:16 UTC; root
Repository: https://kathrinmoellenhoff.r-universe.dev
Date/Publication: 2019-09-27 09:20:11 UTC
RemoteUrl: https://github.com/cran/SimDissolution
RemoteRef: HEAD
RemoteSha: 90171474eb1e27708c0cb547908ae2b3c6209eca