Package: SimDissolution 0.1.0

SimDissolution: Modeling and Assessing Similarity of Drug Dissolutions Profiles

Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.

Authors:Kathrin Moellenhoff

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SimDissolution.pdf |SimDissolution.html✨
SimDissolution/json (API)

# Install 'SimDissolution' in R:
install.packages('SimDissolution', repos = c('https://kathrinmoellenhoff.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.00 score 203 downloads 3 exports 19 dependencies

Last updated 5 years agofrom:90171474eb. Checks:8 OK. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKJan 30 2025
R-4.5-winOKJan 30 2025
R-4.5-macOKJan 30 2025
R-4.5-linuxOKJan 30 2025
R-4.4-winOKJan 30 2025
R-4.4-macOKJan 30 2025
R-4.3-winOKJan 30 2025
R-4.3-macOKJan 30 2025

Exports:f2fit_pharm_modsim_test

Dependencies:alabamaclidplyrfansigenericsgluelifecyclemagrittrmvtnormnumDerivpillarpkgconfigR6rlangtibbletidyselectutf8vctrswithr