Package: SimDissolution 0.1.0

SimDissolution: Modeling and Assessing Similarity of Drug Dissolutions Profiles

Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.

Authors:Kathrin Moellenhoff

SimDissolution_0.1.0.tar.gz
SimDissolution_0.1.0.zip(r-4.7)SimDissolution_0.1.0.zip(r-4.6)SimDissolution_0.1.0.zip(r-4.5)
SimDissolution_0.1.0.tgz(r-4.6-any)SimDissolution_0.1.0.tgz(r-4.5-any)
SimDissolution_0.1.0.tar.gz(r-4.7-any)SimDissolution_0.1.0.tar.gz(r-4.6-any)
SimDissolution_0.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
SimDissolution/json (API)

# Install 'SimDissolution' in R:
install.packages('SimDissolution', repos = c('https://kathrinmoellenhoff.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On CRAN:

Conda:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

1.00 score 145 downloads 3 exports 18 dependencies

Last updated from:90171474eb. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64OK102
source / vignettesOK134
linux-release-x86_64OK111
macos-release-arm64OK101
macos-oldrel-arm64OK107
windows-develOK83
windows-releaseOK76
windows-oldrelOK78
wasm-releaseOK93

Exports:f2fit_pharm_modsim_test

Dependencies:alabamaclidplyrgenericsgluelifecyclemagrittrmvtnormnumDerivpillarpkgconfigR6rlangtibbletidyselectutf8vctrswithr